A Laboratory Exercise for Genotyping Two Human Single Nucleotide Polymorphisms

Autor/inn/en	Fernando, James; Carlson, Bradley; LeBard, Timothy; McCarthy, Michael; Umali, Finianne; Ashton, Bryce; Rose, Ferrill F., Jr.
Titel	A Laboratory Exercise for Genotyping Two Human Single Nucleotide Polymorphisms
Quelle	In: Journal of Biological Education, 50 (2016) 1, S.73-85 (13 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0021-9266
DOI	10.1080/00219266.2015.1007885
Schlagwörter	Genetics; Science Laboratories; Science Instruction; Science Activities; Molecular Biology; Science Experiments; Laboratory Experiments; College Science; College Students; Science Tests; Nebraska + Suchen Sie Ihr Suchwort? Humangenetik; Teaching of science; Science education; Natural sciences Lessons; Naturwissenschaftlicher Unterricht; Molekularbiologie; Laboratory work; Laborarbeit; Collegestudent
Abstract	The dramatic decrease in the cost of sequencing a human genome is leading to an era in which a wide range of students will benefit from having an understanding of human genetic variation. Since over 90% of sequence variation between humans is in the form of single nucleotide polymorphisms (SNPs), a laboratory exercise has been devised in order to illustrate the importance of SNPs. Two separate SNPs are analysed, one of which has a significant effect on a person's phenotype and one which does not. The genotyping protocol is relatively inexpensive and uses standard molecular biology reagents and equipment. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01