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Autor/inSims, Paul A.
TitelUse of a Spreadsheet to Help Students Understand the Origin of the Empirical Equation that Allows Estimation of the Extinction Coefficients of Proteins
QuelleIn: Journal of Chemical Education, 89 (2012) 6, S.738-742 (5 Seiten)Infoseite zur Zeitschrift
PDF als Volltext Verfügbarkeit 
Spracheenglisch
Dokumenttypgedruckt; online; Zeitschriftenaufsatz
ISSN0021-9584
DOI10.1021/ed200600d
SchlagwörterBiochemistry; College Science; Science Instruction; Undergraduate Students; Student Surveys; Science Laboratories; Computation; Spreadsheets; Matrices; Tables (Data); Multiple Regression Analysis; Assignments
AbstractA brief history of the development of the empirical equation that is used by prominent, Internet-based programs to estimate (or calculate) the extinction coefficients of proteins is presented. In addition, an overview of a series of related assignments designed to help students understand the origin of the empirical equation is provided. The assignments culminate in a challenge whereby students were encouraged to develop a similar equation. The results of a student survey suggest that the assignments helped increase understanding of how the empirical equation was developed, in particular, and of the use of statistical methods (e.g., multiple linear regression, nonlinear least-squares fitting), in general. (Contains 2 tables and 1 figure.) (As Provided).
AnmerkungenDivision of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Erfasst vonERIC (Education Resources Information Center), Washington, DC
Update2017/4/10
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