Epigenetics and the Biological Definition of Gene X Environment Interactions

Autor/in	Meaney, Michael J.
Titel	Epigenetics and the Biological Definition of Gene X Environment Interactions
Quelle	In: Child Development, 81 (2010) 1, S.41-79 (40 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0009-3920
DOI	10.1111/j.1467-8624.2009.01381.x
Schlagwörter	Genetics; Cytology; Child Development; Environmental Influences; Perinatal Influences; Developmental Stages; Mothers + Suchen Sie Ihr Suchwort? Humangenetik; Zytologie; Kindesentwicklung; Environmental influence; Umwelteinfluss; Perinatalperiode; Mother; Mutter
Abstract	Variations in phenotype reflect the influence of environmental conditions during development on cellular functions, including that of the genome. The recent integration of epigenetics into developmental psychobiology illustrates the processes by which environmental conditions in early life structurally alter DNA, providing a physical basis for the influence of the perinatal environmental signals on phenotype over the life of the individual. This review focuses on the enduring effects of naturally occurring variations in maternal care on gene expression and phenotype to provide an example of environmentally driven plasticity at the level of the DNA, revealing the interdependence of gene and environmental in the regulation of phenotype. (Contains 6 figures.) (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10