The Broad Autism Phenotype. Findings from an Epidemiological Survey

Autor/inn/en	Micali, N.; Chakrabarti, S.; Fombonne, E.
Titel	The Broad Autism Phenotype. Findings from an Epidemiological Survey
Quelle	In: Autism: The International Journal of Research and Practice, 8 (2004) 1, S.21-37 (17 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1362-3613
DOI	10.1177/1362361304040636
Schlagwörter	Mothers; Depression (Psychology); Anxiety; Autism; Children; Pervasive Developmental Disorders; Questionnaires; Epidemiology + Suchen Sie Ihr Suchwort? Mother; Mutter; Angst; Autismus; Child; Kind; Kinder; Fragebogen; Epidemiologie
Abstract	This study aimed to determine if relatives of children with autism and less severe pervasive developmental disorders (PDDs) have higher rates of various components of the broad autistic phenotype. Psychiatric and medical disorders were investigated. Parents of children with PDDs were selected from an epidemiological survey and compared with parents of control children with non-autistic developmental problems. Rates of abnormalities and disorders were compared in relatives of 79 cases and 61 controls. Medical and autoimmune disorders in both groups were endorsed by few relatives. Specific developmental disorders were commoner in parents of controls. Depression and anxiety were significantly more prevalent in mothers of children with PDDs. Significantly more PDD children had at least one firstdegree relative with anxiety and one second-degree relative with OCD. PDDs were commoner in first-degree relatives. The implications of the findings for the definition of the broad phenotype of autism are discussed. (Author).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10