Moderate Level Alcohol During Pregnancy, Prenatal Stress, or Both and Limbic-Hypothalamic-Pituitary-Adrenocortical Axis Response to Stress in Rhesus Monkeys

Autor/inn/en	Schneider, Mary L.; Moore, Colleen F.; Kraemer, Gary W.
Titel	Moderate Level Alcohol During Pregnancy, Prenatal Stress, or Both and Limbic-Hypothalamic-Pituitary-Adrenocortical Axis Response to Stress in Rhesus Monkeys
Quelle	In: Child Development, 75 (2004) 1, S.96-109 (14 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0009-3920
DOI	10.1111/j.1467-8624.2004.00656.x
Schlagwörter	Pregnancy; Drinking; Stress Variables; Separation Anxiety; Emotional Response; Comparative Analysis; Animals; Animal Behavior; Mothers + Suchen Sie Ihr Suchwort? Schwangerschaft; Trinken; Trennungsangst; Emotionales Verhalten; Animal; Tier; Tiere; Tierverhalten; Mother; Mutter
Abstract	This study examined the relationship between moderate-level prenatal alcohol exposure, prenatal stress, and postnatal response to a challenging event in 6-month-old rhesus monkeys. Forty-one rhesus monkey (Macaca mulatta) infants were exposed prenatally to moderate level alcohol, maternal stress, or both. Offspring plasma cortisol and adrenocorticotrophic hormone (ACTH) were determined from blood samples before maternal separation and after separation. Behavioral observations were made repeatedly across separation. Moderate-level prenatal alcohol exposure was associated with significantly higher plasma ACTH response to maternal separation. Offspring exposed to prenatal alcohol, prenatal stress, and prenatal alcohol and stress showed reduced behavioral adaptation to stress compared with controls. Baseline, 2-hr, and 26-hr plasma ACTH levels were intercorrelated and predicted behavior during separation. (Author).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10