Neuropsychological Correlates of P300 Parameters in Individuals with Aphasia

Autor/inn/en	Choinski, Mateusz; Szelag, Elzbieta; Wolak, Tomasz; Szymaszek, Aneta
Titel	Neuropsychological Correlates of P300 Parameters in Individuals with Aphasia
Quelle	In: International Journal of Language & Communication Disorders, 58 (2023) 2, S.256-269 (14 Seiten) PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Szymaszek, Aneta)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1368-2822
DOI	10.1111/1460-6984.12781
Schlagwörter	Neuropsychology; Brain Hemisphere Functions; Diagnostic Tests; Cognitive Ability; Aphasia; Neurological Impairments; Comparative Analysis; Task Analysis; Cognitive Processes; Physiology; Correlation; Patients; Speech Therapy; Intervention; Short Term Memory; Attention Control; Executive Function; Language Processing + Suchen Sie Ihr Suchwort? Neuropsychologie; Diagnostic test; Diagnostischer Test; Denkfähigkeit; Expressive Aphasie; Aphasie; Neurodegenerative Erkrankung; Aufgabenanalyse; Cognitive process; Kognitiver Prozess; Physiologie; Korrelation; Patient; Entwicklungsproximale Sprachtherapie; Logotherapie; Kurzzeitgedächtnis; Aufmerksamkeitstest; Sprachverarbeitung
Abstract	Background: Aphasia is often accompanied by impairment of non-language cognitive functions. Assessment of cognitive capacity in people with aphasia (PWA) with standard neuropsychological methods may be problematic due to their language difficulties. Numerous experimental studies indicate that P300 may be considered as an index of cognitive capacity in both healthy and clinical samples. Accordingly, the measurement of event-related potentials enables the investigation of behaviourally non-observable mental processes underlying the cognitive functions that are assessed with neuropsychological tests. Aims: To investigate in PWA the relationship between P300 parameters and cognitive function efficiency measured with neuropsychological methods. Methods & Procedures: A total of 25 PWA after left-hemispheric stroke participated in the study. Electrophysiological (EEG) signals were recorded during the performance of a visual Go-No Go task. P300 was identified on nine electrodes, which were then pooled in three lines: left (F3, C3, P3), central (Fz, Cz, Pz) and right (F4, C4, P4). The neuropsychological assessment of cognitive functions included mental speed, short-term memory, divided attention, executive functions, auditory language comprehension and expression. Outcomes & Results: P300 latency correlated with indices of several cognitive functions: temporal resolution, psychomotor speed, spatial short-term memory, planning, word and sentence comprehension, as well as verbal fluency. Shorter P300 latencies were accompanied by greater efficiency of the abovementioned functions. In contrast, significant correlations between P300 amplitudes and cognitive measures were fragmentary. Conclusions & Implications: In PWA, P300 latency might be related to cognitive functioning, especially to measures that rely heavily on the speed of information processing. However, P300 seems to be unrelated to more complex cognitive functions. P300 latency may be used as a neurophysiological correlate of cognitive efficiency in PWA and might have potential applications in monitoring the effects of therapeutic interventions in this patient group. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01