Cognitive and Language Development at Age 4-6 Years in Children HIV-Exposed but Uninfected Compared to Those HIV-Unexposed and to Children Living with HIV

Autor/inn/en	Gruver, Rachel S.; Mall, Sumaya; Kvalsvig, Jane D.; Knox, Justin R.; Mellins, Claude A.; Desmond, Chris; Kauchali, Shuaib; Arpadi, Stephen M.; Taylor, Myra; Davidson, Leslie L.
Titel	Cognitive and Language Development at Age 4-6 Years in Children HIV-Exposed but Uninfected Compared to Those HIV-Unexposed and to Children Living with HIV
Quelle	In: New Directions for Child and Adolescent Development, (2020) 171, S.39-54 (16 Seiten) PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Gruver, Rachel S.) ORCID (Mall, Sumaya) ORCID (Knox, Justin R.)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1520-3247
DOI	10.1002/cad.20351
Schlagwörter	Acquired Immunodeficiency Syndrome (AIDS); Preschool Children; Child Development; Scores; Intelligence Tests; Language Impairments; Language Acquisition; Perinatal Influences; Comparative Analysis; Foreign Countries; Diagnostic Tests; Case Studies; Parent Child Relationship; Mothers; Prevention; South Africa; Kaufman Assessment Battery for Children; Reynell Developmental Language Scales + Suchen Sie Ihr Suchwort? Pre-school age; Preschool age; Child; Children; Pre-school education; Preschool education; Vorschulalter; Kind; Kinder; Vorschulkind; Vorschulkinder; Vorschulerziehung; Vorschule; Kindesentwicklung; Intelligence test; Intelligenztest; Speech disorder; Speech disorders; Speech disabilities; Speech disability; Speech handicap; Speech handicaps; Speech impairment; Speech impairments; Language handicaps; Sprachbehinderung; Sprachaneignung; Spracherwerb; Perinatalperiode; Ausland; Diagnostic test; Diagnostischer Test; Case study; Fallstudie; Case Study; Parents-child relationship; Parent-child-relation; Parent-child relationship; Eltern-Kind-Beziehung; Mother; Mutter; Prävention; Vorbeugung; Südafrika; Süd-Afrika; Republik Südafrika; Südafrikanische Republik
Abstract	Perinatal HIV infection is associated with delayed neurocognitive development, but less is known about children perinatally HIV-exposed but uninfected (CHEU). We compared cognitive and language outcomes in 4-6-year old CHEU versus children HIV-unexposed and uninfected (CHUU) and children living with HIV (CLHIV). We enrolled 1,581 children (77% of the child population) in five communities in KwaZulu-Natal, South Africa. Children completed: Grover-Counter Scale of cognitive development, sub-scales of the Kaufman Assessment Battery for Children, Reynell Developmental Language Scales. HIV status of children and primary caregivers was determined by repeated rapid tests or report of prior testing. We conducted a cross-sectional multivariable linear regression on 922 dyads with complete data (257 CHEU, 627 CHUU, 38 CLHIV). On all outcome measures, CHEU and CHUU groups had comparable scores; CLHIV scored significantly lower. Emerging global progress toward the elimination of vertical HIV transmission may not only reduce mortality, but also positively impact child development. (As Provided).
Anmerkungen	Wiley. Available from: John Wiley & Sons, Inc. 111 River Street, Hoboken, NJ 07030. Tel: 800-835-6770; e-mail: cs-journals@wiley.com; Web site: https://www.wiley.com/en-us
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01