Maternal Systemic Lupus Erythematosus, Rheumatoid Arthritis, and Risk for Autism Spectrum Disorders in Offspring: A Meta-Analysis

Autor/inn/en	Zhu, Zhixian; Tang, Shiming; Deng, Xiaopeng; Wang, Ying
Titel	Maternal Systemic Lupus Erythematosus, Rheumatoid Arthritis, and Risk for Autism Spectrum Disorders in Offspring: A Meta-Analysis
Quelle	In: Journal of Autism and Developmental Disorders, 50 (2020) 8, S.2852-2859 (8 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-020-04400-y
Schlagwörter	Chronic Illness; Special Health Problems; Risk; Autism; Pervasive Developmental Disorders; Mothers; Children; Meta Analysis + Suchen Sie Ihr Suchwort? Chronic disease; Chronische Krankheit; Zivilisationskrankheit; Risiko; Autismus; Mother; Mutter; Child; Kind; Kinder; Meta-analysis; Metaanalyse
Abstract	This study assessed the relationships between maternal systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA) and risk for autism spectrum disorders (ASDs) in offspring. Seven observational studies, including 25,005 ASD cases and 4,543,321 participants, were included for meta-analysis. Pooled results by using random-effects models suggested that maternal RA was associated with an increased risk for ASDs [odds ratio (OR) 1.39, 95% confidence interval (CI) 1.16-1.67], while maternal SLE was associated with an increased risk for ASDs only in western population (OR 1.91, 95% CI 1.02-3.57). Further study is warranted to confirm these results. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01