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Autor/inn/enChristian, MacKinsey A.; Samms-Vaughan, Maureen; Lee, MinJae; Bressler, Jan; Hessabi, Manouchehr; Grove, Megan L.; Shakespeare-Pellington, Sydonnie; Coore Desai, Charlene; Reece, Jody-Ann; Loveland, Katherine A.; Boerwinkle, Eric; Rahbar, Mohammad H.
TitelMaternal Exposures Associated with Autism Spectrum Disorder in Jamaican Children
QuelleIn: Journal of Autism and Developmental Disorders, 48 (2018) 8, S.2766-2778 (13 Seiten)
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Spracheenglisch
Dokumenttypgedruckt; online; Zeitschriftenaufsatz
ISSN0162-3257
DOI10.1007/s10803-018-3537-6
SchlagwörterAutism; Pervasive Developmental Disorders; Pregnancy; Correlation; Mothers; Hazardous Materials; Nutrition; Diseases; Prenatal Influences; Case Studies; Control Groups; Matched Groups; Regression (Statistics); Trauma; Foreign Countries; Children; Jamaica
AbstractAutism spectrum disorder (ASD) is a complex neurodevelopmental disorder with poorly understood etiology. Many maternal exposures during pregnancy and breastfeeding potentially interfere with neurodevelopment. Using data from two age- and sex-matched case-control studies in Jamaica (n = 298 pairs), results of conditional logistic regression analyses suggest that maternal exposures to fever or infection (matched odds ratio (MOR) = 3.12, 95% CI 1.74-5.60), physical trauma (MOR 2.02, 95% CI 1.01-4.05), and oil-based paints (MOR 1.99, 95% CI 1.14-3.46) may be associated with ASD. Additionally, maternal exposure to oil-based paints may modify the relationship between maternal exposure to pesticides and ASD, which deepens our understanding of the association between pesticides and ASD. (As Provided).
AnmerkungenSpringer. Available from: Springer Nature. 233 Spring Street, New York, NY 10013. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-348-4505; e-mail: customerservice@springernature.com; Web site: https://link.springer.com/
Erfasst vonERIC (Education Resources Information Center), Washington, DC
Update2020/1/01
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