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Autor/inn/en | Redmond, Sean M.; Ash, Andrea C. |
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Titel | Associations between the 2D:4D Proxy Biomarker for Prenatal Hormone Exposures and Symptoms of Developmental Language Disorder |
Quelle | In: Journal of Speech, Language, and Hearing Research, 60 (2017) 11, S.3226-3236 (11 Seiten)
PDF als Volltext |
Sprache | englisch |
Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
ISSN | 1092-4388 |
DOI | 10.1044/2017_JSLHR-L-17-0143 |
Schlagwörter | Human Body; Prenatal Influences; Physiology; Etiology; Neurological Impairments; Developmental Disabilities; Males; Language Impairments; Verbal Communication; Nonverbal Communication; Language Tests; Grammar; Clinical Evaluation of Language Fundamentals Menschlicher Körper; Pränataler Einfluss; Physiologie; Ätiologie; Neurodegenerative Erkrankung; Entwicklungsstörung; Male; Männliches Geschlecht; Speech disorder; Speech disorders; Speech disabilities; Speech disability; Speech handicap; Speech handicaps; Speech impairment; Speech impairments; Language handicaps; Sprachbehinderung; Non-verbal communication; Nonverbale Kommunikation; Language test; Sprachtest; Grammatik |
Abstract | Purpose: Relative lengths of the index (2D) and ring (4D) fingers in humans represent a retrospective biomarker of prenatal hormonal exposures. For this reason, the 2D:4D digit ratio can be used to investigate potential hormonal contributions to the etiology of neurodevelopmental disorders. This study tested potential group differences in 2D:4D digit ratios in a sample of boys with and without developmental language disorder (DLD) and examined the strength of associations between 2D:4D digit ratio and a battery of verbal and nonverbal measures. Method: A group of 29 boys affected by DLD and a group of 76 boys with typical language abilities participated (age range = 5;6-11;0 years). Scanned images were used to measure finger lengths. Language measures included the core language subtests from the Clinical Evaluation of Language Fundamentals--Fourth Edition (Semel, Wiig, & Secord, 2003), a nonword repetition task, a sentence recall task, and the Test of Early Grammatical Impairment (Rice & Wexler, 2001). Results: Significant group differences indicated lower 2D:4D digit ratios in the group with DLD. Modest associations were found between 2D:4D digit ratios and some Clinical Evaluation of Language Fundamentals--Fourth Edition subtests. Conclusions: Prenatal hormone exposures may play a role in the etiology of some language symptoms. (As Provided). |
Anmerkungen | American Speech-Language-Hearing Association. 2200 Research Blvd #250, Rockville, MD 20850. Tel: 301-296-5700; Fax: 301-296-8580; e-mail: slhr@asha.org; Web site: http://jslhr.pubs.asha.org |
Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
Update | 2020/1/01 |