Using Next-Generation Sequencing to Explore Genetics and Race in the High School Classroom

Autor/inn/en	Yang, Xinmiao; Hartman, Mark R.; Harrington, Kristin T.; Etson, Candice M.; Fierman, Matthew B.; Slonim, Donna K.; Walt, David R.
Titel	Using Next-Generation Sequencing to Explore Genetics and Race in the High School Classroom
Quelle	In: CBE - Life Sciences Education, 16 (2017) 2, Artikel 22 (7 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1931-7913
DOI	10.1187/cbe.16-09-0281
Schlagwörter	Science Instruction; Secondary School Science; High School Students; Genetics; Race; Biology; Information Science; Learning Modules; Pretests Posttests; Knowledge Level; Student Surveys; Student Attitudes; Science Laboratories; Scientific Concepts; Undergraduate Students; Teaching Methods; Science Experiments; Laboratory Experiments; Stereotypes; Massachusetts + Suchen Sie Ihr Suchwort? Teaching of science; Science education; Natural sciences Lessons; Naturwissenschaftlicher Unterricht; High school; High schools; Student; Students; Oberschule; Schüler; Schülerin; Studentin; Humangenetik; Rasse; Abstammung; Biologie; Informationswissenschaft; Learning module; Lernmodul; Wissensbasis; Schülerbefragung; Schülerverhalten; Teaching method; Lehrmethode; Unterrichtsmethode; Laboratory work; Laborarbeit; Klischee; Master-Studiengang
Abstract	With the development of new sequencing and bioinformatics technologies, concepts relating to personal genomics play an increasingly important role in our society. To promote interest and understanding of sequencing and bioinformatics in the high school classroom, we developed and implemented a laboratory-based teaching module called "The Genetics of Race." This module uses the topic of race to engage students with sequencing and genetics. In the experimental portion of this module, students isolate their own mitochondrial DNA using standard biotechnology techniques and collect next-generation sequencing data to determine which of their classmates are most and least genetically similar to themselves. We evaluated the efficacy of this module by administering a pretest/posttest evaluation to measure student knowledge related to sequencing and bioinformatics, and we also conducted a survey at the conclusion of the module to assess student attitudes. Upon completion of our Genetics of Race module, students demonstrated significant learning gains, with lower-performing students obtaining the highest gains, and developed more positive attitudes toward scientific research. (As Provided).
Anmerkungen	American Society for Cell Biology. 8120 Woodmont Avenue Suite 750, Bethesda, MD 20814-2762. Tel: 301-347-9300; Fax: 301-347-9310; e-mail: ascbinfo@ascb.org; Website: http://www.ascb.org
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01