Maternal Exposure to Occupational Asthmagens during Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development

Autor/inn/en	Singer, Alison B.; Windham, Gayle C.; Croen, Lisa A.; Daniels, Julie L.; Lee, Brian K.; Qian, Yinge; Schendel, Diana E.; Fallin, M. Daniele; Burstyn, Igor
Titel	Maternal Exposure to Occupational Asthmagens during Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development
Quelle	In: Journal of Autism and Developmental Disorders, 46 (2016) 11, S.3458-3468 (11 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-016-2882-6
Schlagwörter	Autism; Pervasive Developmental Disorders; Mothers; Prenatal Influences; Diseases; At Risk Persons; Hazardous Materials; Work Environment; Young Children; Developmental Disabilities; Cognitive Ability; Motor Development; Observation; Diagnostic Tests; Interviews; Coding; Statistical Analysis; Individual Characteristics; Correlation; Regression (Statistics); California; Colorado; Georgia; Maryland; North Carolina; Pennsylvania; Mullen Scales of Early Learning; Autism Diagnostic Observation Schedule + Suchen Sie Ihr Suchwort? Autismus; Mother; Mutter; Pränataler Einfluss; Disease; Krankheit; Risikogruppe; Hazardous substance; Gefahrstoff; Arbeitsmilieu; Frühe Kindheit; Entwicklungsstörung; Denkfähigkeit; Motorische Entwicklung; Beobachtung; Diagnostic test; Diagnostischer Test; Interviewing; Interviewtechnik; Codierung; Programmierung; Statistische Analyse; Personality characteristic; Personality traits; Persönlichkeitsmerkmal; Korrelation; Regression; Regressionsanalyse; Kalifornien
Abstract	Maternal immune activity has been linked to children with autism spectrum disorder (ASD). We examined maternal occupational exposure to asthma-causing agents during pregnancy in relation to ASD risk. Our sample included 463 ASD cases and 710 general population controls from the Study to Explore Early Development whose mothers reported at least one job during pregnancy. Asthmagen exposure was estimated from a published job-exposure matrix. The adjusted odds ratio for ASD comparing asthmagen-exposed to unexposed was 1.39 (95 % CI 0.96-2.02). Maternal workplace asthmagen exposure was not associated with ASD risk in this study, but this result does not exclude some involvement of maternal exposure to asthma-causing agents in ASD. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01