Maternal Infection during Pregnancy and Autism Spectrum Disorders

Autor/inn/en	Zerbo, Ousseny; Qian, Yinge; Yoshida, Cathleen; Grether, Judith K.; Van de Water, Judy; Croen, Lisa A.
Titel	Maternal Infection during Pregnancy and Autism Spectrum Disorders
Quelle	In: Journal of Autism and Developmental Disorders, 45 (2015) 12, S.4015-4025 (11 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-013-2016-3
Schlagwörter	Autism; Pervasive Developmental Disorders; Mothers; Pregnancy; Diseases; Prenatal Influences; Case Studies; Risk; Clinical Diagnosis; Correlation; California + Suchen Sie Ihr Suchwort? Autismus; Mother; Mutter; Schwangerschaft; Disease; Krankheit; Pränataler Einfluss; Case study; Fallstudie; Case Study; Risiko; Korrelation; Kalifornien
Abstract	We conducted a nested case-control study including 407 cases and 2,075 frequency matched controls to investigate the association between maternal infections during pregnancy and risk of autism spectrum disorders (ASD). Cases, controls, and maternal infections were ascertained from Kaiser Permanente Northern California clinical databases. No overall association between diagnoses of any maternal infection during pregnancy and ASD was observed [adjusted odds ratio (OR[subscript adj]) = 1.15, 95 % confidence interval (CI) 0.92-1.43]. However, women with infections diagnosed during a hospital admission (OR[subscript adj] = 1.48, 95 % CI 1.07-2.04), particularly bacterial infections (OR[subscript adj] = 1.58, 95 % CI 1.06-2.37), were at increased risk of delivering a child with ASD. Multiple infections during pregnancy were associated with ASD (OR[subscript adj] = 1.36, 95 % CI 1.05-1.78). (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01