Autism Spectrum Disorder Profile in Neurofibromatosis Type I

Autor/inn/en	Garg, Shruti; Plasschaert, Ellen; Descheemaeker, Mie-Jef; Huson, Susan; Borghgraef, Martine; Vogels, Annick; Evans, D. Gareth; Legius, Eric; Green, Jonathan
Titel	Autism Spectrum Disorder Profile in Neurofibromatosis Type I
Quelle	In: Journal of Autism and Developmental Disorders, 45 (2015) 6, S.1649-1657 (9 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-014-2321-5
Schlagwörter	Pervasive Developmental Disorders; Autism; Profiles; Genetic Disorders; Diagnostic Tests; Observation; Rating Scales; Language Skills; Behavior Patterns; Repetition; Nonverbal Communication; Matched Groups; Intelligence Quotient; Interpersonal Competence; Adolescents; Evidence; Children; Young Children + Suchen Sie Ihr Suchwort? Autismus; Charakterisierung; Profilanalyse; Diagnostic test; Diagnostischer Test; Beobachtung; Rating-Skala; Language skill; Sprachkompetenz; Wiederholung; Non-verbal communication; Nonverbale Kommunikation; Intelligenzquotient; Interpersonale Kompetenz; Adolescent; Adolescence; Adoleszenz; Jugend; Jugendalter; Jugendlicher; Evidenz; Child; Kind; Kinder; Frühe Kindheit
Abstract	Neurofibromatosis Type 1 (NF1) is a common autosomal dominant single-gene disorder, in which the co-occurrence of autism spectrum disorder (ASD) has attracted considerable research interest recently with prevalence estimates of 21-40%. However, detailed characterization of the ASD behavioral phenotype in NF1 is still lacking. This study characterized the phenotypic profile of ASD symptomatology presenting in 4-16 year old children with NF1 (n = 36) using evidence from parent-rated Social Responsiveness Scale and researcher autism diagnostic observation Scale-2. Compared to IQ-matched reference groups of children with autism and ASD, the NF1 profile shows overall similarity but improved eye contact, less repetitive behaviors and better language skills. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01