Engaging with Molecular Form to Understand Function

Autor/inn/en	Barber, Nicola C.; Stark, Louisa A.
Titel	Engaging with Molecular Form to Understand Function
Quelle	In: CBE - Life Sciences Education, 13 (2014) 1, S.21-24 (4 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1931-7913
DOI	10.1187/cbe.13-12-0247
Schlagwörter	Science Instruction; Biochemistry; Genetics; Molecular Structure; Films; Spectroscopy; Web Sites; Animation; Cytology; Internet; Educational Resources + Suchen Sie Ihr Suchwort? Teaching of science; Science education; Natural sciences Lessons; Naturwissenschaftlicher Unterricht; Biochemie; Humangenetik; Film; Spektroskopie; Web-Design; Zytologie; Bildungsmittel
Abstract	Cells are bustling factories with diverse and prolific arrays of molecular machinery. Remarkably, this machinery self-organizes to carry out the complex biochemical activities characteristic of life. When Watson and Crick published the structure of DNA, they noted that DNA base pairing creates a double-stranded form that provides a means of accurately copying the genetic information. Understanding this link between form and function is important for understanding the basis of any biological activity. At the most basic level, a biomolecule's function is dictated by its structure. The molecule's shape and chemical properties facilitate interactions with other molecules and determine its role in the cell. Protein function depends on the precise folding of encoded linear stretches of amino acids into three-dimensional shapes. Protein misfolding can lead to various disease states. In this review, we explore engaging online resources that highlight the connection between structure and function in biomolecules. These resources are particularly relevant for instruction at the advanced high school and undergraduate biology levels. (As Provided).
Anmerkungen	American Society for Cell Biology. 8120 Woodmont Avenue Suite 750, Bethesda, MD 20814-2762. Tel: 301-347-9300; Fax: 301-347-9310; e-mail: ascbinfo@ascb.org; Website: http://www.ascb.org
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10