Research Experience for the Organic Chemistry Laboratory: A Student-Centered Optimization of A Microwave-Enhanced Williamson Ether Synthesis and GC Analysis

Autor/in	Baar, Marsha R.
Titel	Research Experience for the Organic Chemistry Laboratory: A Student-Centered Optimization of A Microwave-Enhanced Williamson Ether Synthesis and GC Analysis
Quelle	In: Journal of Chemical Education, 95 (2018) 7, S.1235-1237 (3 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Baar, Marsha R.)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0021-9584
DOI	10.1021/acs.jchemed.7b00592
Schlagwörter	Organic Chemistry; Student Experience; Student Research; Laboratory Experiments; Synthesis; Cooperative Learning; Student Centered Learning; Hands on Science; Problem Solving; Discovery Learning; Undergraduate Students; Teaching Methods; Pennsylvania + Suchen Sie Ihr Suchwort? Organische Chemie; Studienerfahrung; Studentenforschung; Laboratory work; Laborarbeit; Kooperatives Lernen; Group work; Student-entered learning; Student-centred learning; Student centred learning; Schülerorientierter Unterricht; Schülerzentrierter Unterricht; Gruppenarbeit; Problemlösen; Entdeckendes Lernen; Teaching method; Lehrmethode; Unterrichtsmethode
Abstract	An inquiry-based experiment for the organic chemistry laboratory was developed to provide students with a cognitively rich research experience. Student teams were charged with optimizing the reaction conditions for the Williamson ether synthesis of 2- fluorophenetole from 2-fluorophenol, ethyl bromide, and potassium carbonate in either absolute ethanol or acetonitrile. Microwave acceleration of this S[subscript N]2 reaction followed by rapid GC-MS analysis allowed students to review results, revise experimental conditions, and repeat the modified reaction and its analysis within a 3 h laboratory period. Variables that could be manipulated were reagent equivalencies, solvents and their volume, microwave reaction time, temperature, and wattage. Post-laboratory, all team data were available to the entire class for additional evaluation and each student was required to suggest new conditions for improvement in his/her laboratory report. (As Provided).
Anmerkungen	Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01