a-Band Oscillations in Intracellular Membrane Potentials of Dentate Gyrus Neurons in Awake Rodents

Autor/inn/en	Anderson, Ross W.; Strowbridge, Ben W.
Titel	a-Band Oscillations in Intracellular Membrane Potentials of Dentate Gyrus Neurons in Awake Rodents
Quelle	In: Learning & Memory, 21 (2014) 12, S.656-661 (6 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1072-0502
DOI	10.1101/lm.036269.114
Schlagwörter	Animals; Brain Hemisphere Functions; Memory; Spatial Ability; Neurological Organization; Motion; Responses; Behavioral Science Research + Suchen Sie Ihr Suchwort? Animal; Tier; Tiere; Gedächtnis; Räumliches Vorstellungsvermögen; Bewegungsablauf
Abstract	The hippocampus and dentate gyrus play critical roles in processing declarative memories and spatial information. Dentate granule cells, the first relay in the trisynaptic circuit through the hippocampus, exhibit low spontaneous firing rates even during locomotion. Using intracellular recordings from dentate neurons in awake mice operating a levitated spherical treadmill, we found a transient membrane potential a-band oscillation associated with the onset of spontaneous motion, especially forward walking movements. While often subthreshold, a oscillations could regulate spike timing during locomotion and may enable dentate gyrus neurons to respond to specific cortical afferent pathways while maintaining low average firing rates. (As Provided).
Anmerkungen	Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; Tel: 516-367-8800; Fax: 516-422-4097; e-mail: cshpres@cshl.edu; Web site: http://www.learnmem.org/
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10