An fMRI Investigation of Posttraumatic Flashbacks

Autor/inn/en	Whalley, Matthew G.; Kroes, Marijn C. W.; Huntley, Zoe; Rugg, Michael D.; Davis, Simon W.; Brewin, Chris R.
Titel	An fMRI Investigation of Posttraumatic Flashbacks
Quelle	In: Brain and Cognition, 81 (2013) 1, S.151-159 (9 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0278-2626
DOI	10.1016/j.bandc.2012.10.002
Schlagwörter	Depression (Psychology); Posttraumatic Stress Disorder; Diagnostic Tests; Neurological Impairments; Stimuli; Memory; Brain Hemisphere Functions + Suchen Sie Ihr Suchwort? Diagnostic test; Diagnostischer Test; Neurodegenerative Erkrankung; Anreizsystem; Gedächtnis
Abstract	Flashbacks are a defining feature of posttraumatic stress disorder (PTSD), but there have been few studies of their neural basis. We tested predictions from a dual representation model of PTSD that, compared with ordinary episodic memories of the same traumatic event, flashbacks would be associated with activity in dorsal visual stream and related areas rather than in the medial temporal lobe. Participants with PTSD, with depression but not PTSD, and healthy controls were scanned during a recognition task with personally relevant stimuli. The contrast of flashbacks versus ordinary episodic trauma memories in PTSD was associated with increased activation in sensory and motor areas including the insula, precentral gyrus, supplementary motor area, and mid-occipital cortex. The same contrast was associated with decreased activation in the midbrain, parahippocampal gyrus, and precuneus/posterior cingulate cortex. The results were discussed in terms of theories of PTSD and dual-process models of recognition. (Contains 5 tables and 4 figures.) (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10